| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BPLAN_423 | eno | BPLAN_423 | BPLAN_372 | Conserved hypothetical protein. | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.564 |
| BPLAN_423 | gmk | BPLAN_423 | BPLAN_343 | Conserved hypothetical protein. | Guanylate kinase (GMP kinase); Essential for recycling GMP and indirectly, cGMP. | 0.669 |
| BPLAN_423 | pyrE | BPLAN_423 | BPLAN_128 | Conserved hypothetical protein. | Bifunctional orotate phosphoribosyltransferase/orotidine 5'-phosphate decarboxylase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.565 |
| eno | BPLAN_423 | BPLAN_372 | BPLAN_423 | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Conserved hypothetical protein. | 0.564 |
| eno | gmk | BPLAN_372 | BPLAN_343 | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Guanylate kinase (GMP kinase); Essential for recycling GMP and indirectly, cGMP. | 0.593 |
| eno | purL | BPLAN_372 | BPLAN_153 | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Phosphoribosylformylglycinamidine synthase; COG0046; Protein involved in 'de novo' IMP biosynthetic process. | 0.484 |
| gmk | BPLAN_423 | BPLAN_343 | BPLAN_423 | Guanylate kinase (GMP kinase); Essential for recycling GMP and indirectly, cGMP. | Conserved hypothetical protein. | 0.669 |
| gmk | eno | BPLAN_343 | BPLAN_372 | Guanylate kinase (GMP kinase); Essential for recycling GMP and indirectly, cGMP. | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.593 |
| gmk | guaA | BPLAN_343 | BPLAN_161 | Guanylate kinase (GMP kinase); Essential for recycling GMP and indirectly, cGMP. | Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP. | 0.960 |
| gmk | ndk | BPLAN_343 | BPLAN_187 | Guanylate kinase (GMP kinase); Essential for recycling GMP and indirectly, cGMP. | Nucleoside-diphosphate kinase; COG0105. | 0.919 |
| gmk | nrdE | BPLAN_343 | BPLAN_330 | Guanylate kinase (GMP kinase); Essential for recycling GMP and indirectly, cGMP. | Ribonucleotide-diphosphate reductase subunit alpha; COG0209; Protein involved in class I ribonucleotide reductase activity. | 0.913 |
| gmk | prsA | BPLAN_343 | BPLAN_142 | Guanylate kinase (GMP kinase); Essential for recycling GMP and indirectly, cGMP. | Ribose-phosphate pyrophosphokinase; COG0462; Protein involved in purine ribonucleotide biosynthetic process. | 0.574 |
| gmk | purB | BPLAN_343 | BPLAN_152 | Guanylate kinase (GMP kinase); Essential for recycling GMP and indirectly, cGMP. | Adenylosuccinate lyase; COG0015; Protein involved in purine ribonucleotide biosynthetic process; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.917 |
| gmk | purL | BPLAN_343 | BPLAN_153 | Guanylate kinase (GMP kinase); Essential for recycling GMP and indirectly, cGMP. | Phosphoribosylformylglycinamidine synthase; COG0046; Protein involved in 'de novo' IMP biosynthetic process. | 0.675 |
| gmk | pyrE | BPLAN_343 | BPLAN_128 | Guanylate kinase (GMP kinase); Essential for recycling GMP and indirectly, cGMP. | Bifunctional orotate phosphoribosyltransferase/orotidine 5'-phosphate decarboxylase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.650 |
| gmk | surE | BPLAN_343 | BPLAN_149 | Guanylate kinase (GMP kinase); Essential for recycling GMP and indirectly, cGMP. | Acid phosphatase, survival protein; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.913 |
| guaA | gmk | BPLAN_161 | BPLAN_343 | Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP. | Guanylate kinase (GMP kinase); Essential for recycling GMP and indirectly, cGMP. | 0.960 |
| guaA | ndk | BPLAN_161 | BPLAN_187 | Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP. | Nucleoside-diphosphate kinase; COG0105. | 0.539 |
| guaA | nrdE | BPLAN_161 | BPLAN_330 | Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP. | Ribonucleotide-diphosphate reductase subunit alpha; COG0209; Protein involved in class I ribonucleotide reductase activity. | 0.508 |
| guaA | prsA | BPLAN_161 | BPLAN_142 | Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP. | Ribose-phosphate pyrophosphokinase; COG0462; Protein involved in purine ribonucleotide biosynthetic process. | 0.719 |