Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mrcABifunctional transglycosylase/transpeptidase penicillin-binding protein; COG5009. (771 aa)    
Predicted Functional Partners:
mrdA
Putative penicillin-binding protein 2; COG0768; Protein involved in peptidoglycan biosynthetic process.
 
 
 0.971
ftsI
FtsI-like transpeptidase/penicillin-binding protein; COG0768.
 
 
 0.965
serA
Putative phosphoglycerate dehydrogenase; COG0111; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
       0.763
BPLAN_355
Putative PSP1 domain-containing protein; COG1774.
       0.722
BPLAN_543
Conserved hypothetical protein.
    
 
 0.695
murC
UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
 
   
 0.622
BPLAN_091
Signal peptidase I; COG0681; Protein involved in protein secretion; Belongs to the peptidase S26 family.
  
     0.520
mrdB
Cell cycle protein; COG0772; Protein involved in regulation of cell shape; Belongs to the SEDS family.
  
 
 
 0.518
mraY
phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.
 
  
 0.514
coaD
Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.
       0.501
Your Current Organism:
Blattabacterium sp. BPLAN
NCBI taxonomy Id: 600809
Other names: B. sp. (Periplaneta americana) str. BPLAN, Blattabacterium sp. (Periplaneta americana) str. BPLAN, Blattabacterium sp. (Periplaneta americana) strain BPLAN
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