STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cysECOG1045; Protein involved in serine O-acetyltransferase activity. (277 aa)    
Predicted Functional Partners:
cysK
Cysteine synthase A; COG0031; Protein involved in cysteine biosynthetic process from serine; Belongs to the cysteine synthase/cystathionine beta- synthase family.
 
 0.994
cysS
COG0215; Protein involved in cysteinyl-tRNA aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family.
 
  
 0.962
thrA
Aspartokinase/homoserine dehydrogenase; COG0527.
    
 0.874
metB
Cystathionine gamma-synthase; COG0626; Protein involved in acetate biosynthetic process.
  
 
 0.871
thrB
Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
     
 0.816
ilvA
Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
     
  0.800
pgsA
CDP-diacylglycerol--serine O-phosphatidyltransferase; COG1183.
     
  0.800
trpA
Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
     
  0.800
cysG
Siroheme synthase; COG0007; Protein involved in siroheme biosynthetic process.
       0.742
cysJ
Sulfite reductase; COG0369.
     
 0.642
Your Current Organism:
Blattabacterium sp. BPLAN
NCBI taxonomy Id: 600809
Other names: B. sp. (Periplaneta americana) str. BPLAN, Blattabacterium sp. (Periplaneta americana) str. BPLAN, Blattabacterium sp. (Periplaneta americana) strain BPLAN
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