Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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Score
lpdACOG1249; Protein involved in dihydrolipoamide metabolic process. (462 aa)    
Predicted Functional Partners:
aceF
Dihydrolipoamide acyltransferase E2 component; COG0508.
  0.997
sucB-2
2-oxoglutarate dehydrogenase complex, dihydrolipoamide succinyltransferase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).
 
  0.996
sucA
2-oxoglutarate dehydrogenase E1 component; COG0022.
  
 0.996
gcvP
COG1003; Protein involved in glycine decarboxylation via glycine cleavage system; Belongs to the GcvP family.
  
 0.995
kgd
2-oxoglutarate dehydrogenase, E1 component; COG0567.
  
 0.995
sucB
2-oxoglutarate dehydrogenase, E2 component; COG0508.
 
  0.988
pdhB
Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
  
 0.985
gcvT
Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine.
  
 0.964
gcvH
Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
   
 0.961
acoA
Pyruvate dehydrogenase E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
  
 
 0.958
Your Current Organism:
Blattabacterium sp. BPLAN
NCBI taxonomy Id: 600809
Other names: B. sp. (Periplaneta americana) str. BPLAN, Blattabacterium sp. (Periplaneta americana) str. BPLAN, Blattabacterium sp. (Periplaneta americana) strain BPLAN
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