| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| aroC | deaD | BPLAN_450 | BPLAN_449 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | ATP-dependent RNA helicase; COG051; Belongs to the DEAD box helicase family. | 0.778 |
| aroC | mdtK | BPLAN_450 | BPLAN_448 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | NorM-like multidrug efflux protein; COG0534; Protein involved in response to drug. | 0.519 |
| aroC | miaA | BPLAN_450 | BPLAN_451 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | 0.789 |
| deaD | aroC | BPLAN_449 | BPLAN_450 | ATP-dependent RNA helicase; COG051; Belongs to the DEAD box helicase family. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.778 |
| deaD | mdtK | BPLAN_449 | BPLAN_448 | ATP-dependent RNA helicase; COG051; Belongs to the DEAD box helicase family. | NorM-like multidrug efflux protein; COG0534; Protein involved in response to drug. | 0.528 |
| deaD | miaA | BPLAN_449 | BPLAN_451 | ATP-dependent RNA helicase; COG051; Belongs to the DEAD box helicase family. | tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | 0.774 |
| deaD | rpsA | BPLAN_449 | BPLAN_329 | ATP-dependent RNA helicase; COG051; Belongs to the DEAD box helicase family. | 30S ribosomal protein S1; COG0539. | 0.875 |
| deaD | topA | BPLAN_449 | BPLAN_339 | ATP-dependent RNA helicase; COG051; Belongs to the DEAD box helicase family. | Putative DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing [...] | 0.425 |
| gapA | mdtK | BPLAN_590 | BPLAN_448 | COG0057; Protein involved in glyceraldehyde-3-phosphate metabolic process; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | NorM-like multidrug efflux protein; COG0534; Protein involved in response to drug. | 0.566 |
| gapA | rpsA | BPLAN_590 | BPLAN_329 | COG0057; Protein involved in glyceraldehyde-3-phosphate metabolic process; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | 30S ribosomal protein S1; COG0539. | 0.549 |
| gcvT | idi | BPLAN_447 | BPLAN_445 | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine. | Putative isopentenyl-diphosphate delta-isomerase; COG1443. | 0.716 |
| gcvT | mdtK | BPLAN_447 | BPLAN_448 | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine. | NorM-like multidrug efflux protein; COG0534; Protein involved in response to drug. | 0.481 |
| gcvT | sscR | BPLAN_447 | BPLAN_446 | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine. | 6-pyruvoyl tetrahydrobiopterin synthase; COG0720. | 0.781 |
| idi | gcvT | BPLAN_445 | BPLAN_447 | Putative isopentenyl-diphosphate delta-isomerase; COG1443. | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine. | 0.716 |
| idi | mdtK | BPLAN_445 | BPLAN_448 | Putative isopentenyl-diphosphate delta-isomerase; COG1443. | NorM-like multidrug efflux protein; COG0534; Protein involved in response to drug. | 0.454 |
| idi | sscR | BPLAN_445 | BPLAN_446 | Putative isopentenyl-diphosphate delta-isomerase; COG1443. | 6-pyruvoyl tetrahydrobiopterin synthase; COG0720. | 0.728 |
| mdtK | aroC | BPLAN_448 | BPLAN_450 | NorM-like multidrug efflux protein; COG0534; Protein involved in response to drug. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.519 |
| mdtK | deaD | BPLAN_448 | BPLAN_449 | NorM-like multidrug efflux protein; COG0534; Protein involved in response to drug. | ATP-dependent RNA helicase; COG051; Belongs to the DEAD box helicase family. | 0.528 |
| mdtK | gapA | BPLAN_448 | BPLAN_590 | NorM-like multidrug efflux protein; COG0534; Protein involved in response to drug. | COG0057; Protein involved in glyceraldehyde-3-phosphate metabolic process; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | 0.566 |
| mdtK | gcvT | BPLAN_448 | BPLAN_447 | NorM-like multidrug efflux protein; COG0534; Protein involved in response to drug. | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine. | 0.481 |