Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
acoAPyruvate dehydrogenase E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (334 aa)    
Predicted Functional Partners:
pdhB
Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
 0.999
aceF
Dihydrolipoamide acyltransferase E2 component; COG0508.
 
 0.994
lpdA
COG1249; Protein involved in dihydrolipoamide metabolic process.
  
 
 0.958
lpdA-2
COG1249; Protein involved in dihydrolipoamide metabolic process.
  
 
 0.958
maeB
Putative NADP-dependent malic enzyme; COG0281; Protein involved in phosphate acetyltransferase activity.
  
 
 0.956
sucA
2-oxoglutarate dehydrogenase E1 component; COG0022.
 
 0.920
pck
Phosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
   
 
  0.839
leuA
2-isopropylmalate synthase; COG0119; Protein involved in leucine biosynthetic process; Belongs to the alpha-IPM synthase/homocitrate synthase family.
   
 
 0.822
fbaA
Fructose 1, 6-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.
  
 
 0.815
ilvB
Putative acetolactate synthase large subunit; COG0028; Protein involved in valine biosynthetic process.
  
 
 0.811
Your Current Organism:
Blattabacterium sp. BPLAN
NCBI taxonomy Id: 600809
Other names: B. sp. (Periplaneta americana) str. BPLAN, Blattabacterium sp. (Periplaneta americana) str. BPLAN, Blattabacterium sp. (Periplaneta americana) strain BPLAN
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