STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
acoAPyruvate dehydrogenase E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (334 aa)    
Predicted Functional Partners:
pdhB
Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
 0.999
aceF
Dihydrolipoamide acyltransferase E2 component; COG0508.
 
  0.996
lpdA
COG1249; Protein involved in dihydrolipoamide metabolic process.
  
 
 0.976
lpdA-2
COG1249; Protein involved in dihydrolipoamide metabolic process.
  
 
 0.976
sucA
2-oxoglutarate dehydrogenase E1 component; COG0022.
 0.958
maeB
Putative NADP-dependent malic enzyme; COG0281; Protein involved in phosphate acetyltransferase activity.
  
 
 0.957
sucB
2-oxoglutarate dehydrogenase, E2 component; COG0508.
  
  0.835
sucB-2
2-oxoglutarate dehydrogenase complex, dihydrolipoamide succinyltransferase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).
  
  0.835
pck
Phosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
   
 
 0.827
leuA
2-isopropylmalate synthase; COG0119; Protein involved in leucine biosynthetic process; Belongs to the alpha-IPM synthase/homocitrate synthase family.
   
 
 0.822
Your Current Organism:
Blattabacterium sp. BPLAN
NCBI taxonomy Id: 600809
Other names: B. sp. (Periplaneta americana) str. BPLAN, Blattabacterium sp. (Periplaneta americana) str. BPLAN, Blattabacterium sp. (Periplaneta americana) strain BPLAN
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