Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ppnKInorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (294 aa)    
Predicted Functional Partners:
nadD
Nicotinic acid mononucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
 
 
 0.939
nadE
NH(3)-dependent NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
    
 0.929
ispU
Undecaprenyl diphosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
     
 0.638
maeB
Putative NADP-dependent malic enzyme; COG0281; Protein involved in phosphate acetyltransferase activity.
   
 
 0.588
BPLAN_550
Conserved hypothetical protein; COG1187; Belongs to the pseudouridine synthase RsuA family.
       0.549
aroD
3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.
  
    0.542
dedA
Putative membrane-associated protein; COG0586.
    
  0.527
mvaK
Mevalonate kinase; COG1577.
     
 0.523
BPLAN_546
Outer membrane protein; COG4775.
       0.510
rnr
Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
   
  0.476
Your Current Organism:
Blattabacterium sp. BPLAN
NCBI taxonomy Id: 600809
Other names: B. sp. (Periplaneta americana) str. BPLAN, Blattabacterium sp. (Periplaneta americana) str. BPLAN, Blattabacterium sp. (Periplaneta americana) strain BPLAN
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.