| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BPLAN_546 | ispU | BPLAN_546 | BPLAN_547 | Outer membrane protein; COG4775. | Undecaprenyl diphosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. | 0.607 |
| BPLAN_546 | ppnK | BPLAN_546 | BPLAN_548 | Outer membrane protein; COG4775. | Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.453 |
| BPLAN_550 | aroD | BPLAN_550 | BPLAN_551 | Conserved hypothetical protein; COG1187; Belongs to the pseudouridine synthase RsuA family. | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | 0.780 |
| BPLAN_550 | ispU | BPLAN_550 | BPLAN_547 | Conserved hypothetical protein; COG1187; Belongs to the pseudouridine synthase RsuA family. | Undecaprenyl diphosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. | 0.420 |
| BPLAN_550 | mvaK | BPLAN_550 | BPLAN_549 | Conserved hypothetical protein; COG1187; Belongs to the pseudouridine synthase RsuA family. | Mevalonate kinase; COG1577. | 0.791 |
| BPLAN_550 | ppnK | BPLAN_550 | BPLAN_548 | Conserved hypothetical protein; COG1187; Belongs to the pseudouridine synthase RsuA family. | Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.557 |
| aroD | BPLAN_550 | BPLAN_551 | BPLAN_550 | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | Conserved hypothetical protein; COG1187; Belongs to the pseudouridine synthase RsuA family. | 0.780 |
| aroD | mvaK | BPLAN_551 | BPLAN_549 | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | Mevalonate kinase; COG1577. | 0.774 |
| aroD | ppnK | BPLAN_551 | BPLAN_548 | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.541 |
| dedA | ppnK | BPLAN_145 | BPLAN_548 | Putative membrane-associated protein; COG0586. | Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.518 |
| ispU | BPLAN_546 | BPLAN_547 | BPLAN_546 | Undecaprenyl diphosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. | Outer membrane protein; COG4775. | 0.607 |
| ispU | BPLAN_550 | BPLAN_547 | BPLAN_550 | Undecaprenyl diphosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. | Conserved hypothetical protein; COG1187; Belongs to the pseudouridine synthase RsuA family. | 0.420 |
| ispU | mvaK | BPLAN_547 | BPLAN_549 | Undecaprenyl diphosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. | Mevalonate kinase; COG1577. | 0.429 |
| ispU | ppnK | BPLAN_547 | BPLAN_548 | Undecaprenyl diphosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. | Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.596 |
| maeB | ppnK | BPLAN_230 | BPLAN_548 | Putative NADP-dependent malic enzyme; COG0281; Protein involved in phosphate acetyltransferase activity. | Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.568 |
| mvaK | BPLAN_550 | BPLAN_549 | BPLAN_550 | Mevalonate kinase; COG1577. | Conserved hypothetical protein; COG1187; Belongs to the pseudouridine synthase RsuA family. | 0.791 |
| mvaK | aroD | BPLAN_549 | BPLAN_551 | Mevalonate kinase; COG1577. | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | 0.774 |
| mvaK | ispU | BPLAN_549 | BPLAN_547 | Mevalonate kinase; COG1577. | Undecaprenyl diphosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. | 0.429 |
| mvaK | ppnK | BPLAN_549 | BPLAN_548 | Mevalonate kinase; COG1577. | Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.520 |
| nadD | nadE | BPLAN_313 | BPLAN_069 | Nicotinic acid mononucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | NH(3)-dependent NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | 0.923 |