| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BPLAN_317 | ribC | BPLAN_317 | BPLAN_558 | 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. Belongs to the DHBP synthase family. | Riboflavin synthase subunit alpha; COG0307; Protein involved in riboflavin biosynthetic process. | 0.996 |
| BPLAN_317 | ribD | BPLAN_317 | BPLAN_491 | 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. Belongs to the DHBP synthase family. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.999 |
| BPLAN_317 | ribE | BPLAN_317 | BPLAN_094 | 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. Belongs to the DHBP synthase family. | Riboflavin synthase subunit beta; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.996 |
| hisI | ribC | BPLAN_200 | BPLAN_558 | Imidazole glycerol-phosphate dehydratase/histidinol phosphatase; COG0139; Protein involved in phosphoribosyl-ATP diphosphatase activity; In the N-terminal section; belongs to the PRA-CH family. | Riboflavin synthase subunit alpha; COG0307; Protein involved in riboflavin biosynthetic process. | 0.659 |
| hisI | ribD | BPLAN_200 | BPLAN_491 | Imidazole glycerol-phosphate dehydratase/histidinol phosphatase; COG0139; Protein involved in phosphoribosyl-ATP diphosphatase activity; In the N-terminal section; belongs to the PRA-CH family. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.416 |
| hisI | rpmE2 | BPLAN_200 | BPLAN_523 | Imidazole glycerol-phosphate dehydratase/histidinol phosphatase; COG0139; Protein involved in phosphoribosyl-ATP diphosphatase activity; In the N-terminal section; belongs to the PRA-CH family. | 50S ribosomal protein L31; COG0254. | 0.825 |
| pdxA | ribC | BPLAN_559 | BPLAN_558 | COG1995; Protein involved in 4-hydroxythreonine-4-phosphate dehydrogenase activity; Belongs to the PdxA family. | Riboflavin synthase subunit alpha; COG0307; Protein involved in riboflavin biosynthetic process. | 0.605 |
| ribC | BPLAN_317 | BPLAN_558 | BPLAN_317 | Riboflavin synthase subunit alpha; COG0307; Protein involved in riboflavin biosynthetic process. | 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. Belongs to the DHBP synthase family. | 0.996 |
| ribC | hisI | BPLAN_558 | BPLAN_200 | Riboflavin synthase subunit alpha; COG0307; Protein involved in riboflavin biosynthetic process. | Imidazole glycerol-phosphate dehydratase/histidinol phosphatase; COG0139; Protein involved in phosphoribosyl-ATP diphosphatase activity; In the N-terminal section; belongs to the PRA-CH family. | 0.659 |
| ribC | pdxA | BPLAN_558 | BPLAN_559 | Riboflavin synthase subunit alpha; COG0307; Protein involved in riboflavin biosynthetic process. | COG1995; Protein involved in 4-hydroxythreonine-4-phosphate dehydrogenase activity; Belongs to the PdxA family. | 0.605 |
| ribC | ribD | BPLAN_558 | BPLAN_491 | Riboflavin synthase subunit alpha; COG0307; Protein involved in riboflavin biosynthetic process. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.999 |
| ribC | ribE | BPLAN_558 | BPLAN_094 | Riboflavin synthase subunit alpha; COG0307; Protein involved in riboflavin biosynthetic process. | Riboflavin synthase subunit beta; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.998 |
| ribC | ribF | BPLAN_558 | BPLAN_562 | Riboflavin synthase subunit alpha; COG0307; Protein involved in riboflavin biosynthetic process. | Riboflavin biosynthesis protein; COG0196; Protein involved in FMN biosynthetic process; Belongs to the ribF family. | 0.919 |
| ribC | rpmE2 | BPLAN_558 | BPLAN_523 | Riboflavin synthase subunit alpha; COG0307; Protein involved in riboflavin biosynthetic process. | 50S ribosomal protein L31; COG0254. | 0.554 |
| ribD | BPLAN_317 | BPLAN_491 | BPLAN_317 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. Belongs to the DHBP synthase family. | 0.999 |
| ribD | hisI | BPLAN_491 | BPLAN_200 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Imidazole glycerol-phosphate dehydratase/histidinol phosphatase; COG0139; Protein involved in phosphoribosyl-ATP diphosphatase activity; In the N-terminal section; belongs to the PRA-CH family. | 0.416 |
| ribD | ribC | BPLAN_491 | BPLAN_558 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Riboflavin synthase subunit alpha; COG0307; Protein involved in riboflavin biosynthetic process. | 0.999 |
| ribD | ribE | BPLAN_491 | BPLAN_094 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Riboflavin synthase subunit beta; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.993 |
| ribD | ribF | BPLAN_491 | BPLAN_562 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Riboflavin biosynthesis protein; COG0196; Protein involved in FMN biosynthetic process; Belongs to the ribF family. | 0.643 |
| ribE | BPLAN_317 | BPLAN_094 | BPLAN_317 | Riboflavin synthase subunit beta; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. Belongs to the DHBP synthase family. | 0.996 |