| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BPLAN_568 | leuA | BPLAN_568 | BPLAN_567 | Conserved hypothetical protein; COG1793. | 2-isopropylmalate synthase; COG0119; Protein involved in leucine biosynthetic process; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.638 |
| BPLAN_568 | leuB | BPLAN_568 | BPLAN_564 | Conserved hypothetical protein; COG1793. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. | 0.653 |
| BPLAN_568 | leuC | BPLAN_568 | BPLAN_566 | Conserved hypothetical protein; COG1793. | 3-isopropylmalate isomerase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.596 |
| BPLAN_568 | leuD | BPLAN_568 | BPLAN_565 | Conserved hypothetical protein; COG1793. | 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.649 |
| leuA | BPLAN_568 | BPLAN_567 | BPLAN_568 | 2-isopropylmalate synthase; COG0119; Protein involved in leucine biosynthetic process; Belongs to the alpha-IPM synthase/homocitrate synthase family. | Conserved hypothetical protein; COG1793. | 0.638 |
| leuA | leuB | BPLAN_567 | BPLAN_564 | 2-isopropylmalate synthase; COG0119; Protein involved in leucine biosynthetic process; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. | 0.980 |
| leuA | leuC | BPLAN_567 | BPLAN_566 | 2-isopropylmalate synthase; COG0119; Protein involved in leucine biosynthetic process; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 3-isopropylmalate isomerase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.998 |
| leuA | leuD | BPLAN_567 | BPLAN_565 | 2-isopropylmalate synthase; COG0119; Protein involved in leucine biosynthetic process; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.995 |
| leuB | BPLAN_568 | BPLAN_564 | BPLAN_568 | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. | Conserved hypothetical protein; COG1793. | 0.653 |
| leuB | leuA | BPLAN_564 | BPLAN_567 | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. | 2-isopropylmalate synthase; COG0119; Protein involved in leucine biosynthetic process; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.980 |
| leuB | leuC | BPLAN_564 | BPLAN_566 | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. | 3-isopropylmalate isomerase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.999 |
| leuB | leuD | BPLAN_564 | BPLAN_565 | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. | 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.999 |
| leuC | BPLAN_568 | BPLAN_566 | BPLAN_568 | 3-isopropylmalate isomerase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | Conserved hypothetical protein; COG1793. | 0.596 |
| leuC | leuA | BPLAN_566 | BPLAN_567 | 3-isopropylmalate isomerase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 2-isopropylmalate synthase; COG0119; Protein involved in leucine biosynthetic process; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.998 |
| leuC | leuB | BPLAN_566 | BPLAN_564 | 3-isopropylmalate isomerase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. | 0.999 |
| leuC | leuD | BPLAN_566 | BPLAN_565 | 3-isopropylmalate isomerase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.999 |
| leuD | BPLAN_568 | BPLAN_565 | BPLAN_568 | 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | Conserved hypothetical protein; COG1793. | 0.649 |
| leuD | leuA | BPLAN_565 | BPLAN_567 | 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 2-isopropylmalate synthase; COG0119; Protein involved in leucine biosynthetic process; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.995 |
| leuD | leuB | BPLAN_565 | BPLAN_564 | 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. | 0.999 |
| leuD | leuC | BPLAN_565 | BPLAN_566 | 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 3-isopropylmalate isomerase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.999 |
