Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
trxBThioredoxin reductase; COG0492; Protein involved in oxidation reduction. (316 aa)    
Predicted Functional Partners:
trxA
Thioredoxin; COG0526; Protein involved in oxidation reduction; Belongs to the thioredoxin family.
 
 
 0.975
sufS
COG0520; Protein involved in cysteine desulfurase activity; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.
  
 
  0.904
ahpC
Alkyl hydroperoxide reductase, subunit C; COG0450; Protein involved in peroxiredoxin activity.
  
 
 0.819
BPLAN_169
Thioredoxin; COG0526.
  
 
 0.770
glyS
glycyl-tRNA synthetase; COG0423.
       0.743
BPLAN_589
Conserved hypothetical protein; COG1091.
       0.563
secD
Bifunctional-export transmembrane SecDF protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily.
  
  
 0.540
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
 0.490
rpsA
30S ribosomal protein S1; COG0539.
 
    0.412
lpxC
UDP-3-O-acyl-N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
     
 0.408
Your Current Organism:
Blattabacterium sp. BPLAN
NCBI taxonomy Id: 600809
Other names: B. sp. (Periplaneta americana) str. BPLAN, Blattabacterium sp. (Periplaneta americana) str. BPLAN, Blattabacterium sp. (Periplaneta americana) strain BPLAN
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