STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
metAAHomoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. (310 aa)    
Predicted Functional Partners:
SDW09232.1
O-acetylhomoserine sulfhydrylase.
 
 
 0.986
SDW07977.1
Cystathionine gamma-synthase.
 
 
 0.966
SDW06857.1
O-succinylhomoserine sulfhydrylase.
 
 
 0.964
SDW87113.1
Homoserine dehydrogenase.
  
 
 0.949
MetF
5,10-methylenetetrahydrofolate reductase (NAD(P)); Belongs to the methylenetetrahydrofolate reductase family.
  
  
 0.872
SDW45999.1
Pimeloyl-ACP methyl ester carboxylesterase.
       0.867
SDW49874.1
Methylenetetrahydrofolate reductase (NADPH).
  
  
 0.858
ilvA
L-threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
  
 
 0.842
SDW17184.1
Threonine dehydratase.
   
 
 0.821
SDW87260.1
L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family.
     
 0.819
Your Current Organism:
Sulfitobacter pontiacus
NCBI taxonomy Id: 60137
Other names: DSM 10014, JCM 21789, S. pontiacus, VKM B-2022, strain ChLG 10
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