STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A1V6NWK1NACHT domain-containing protein. (214 aa)    
Predicted Functional Partners:
A0A1V6NBE2
TPR_REGION domain-containing protein.
    
 0.970
A0A1V6NDF4
WD_REPEATS_REGION domain-containing protein.
    
 0.868
A0A1V6NP01
SPRY domain-containing protein.
    
 0.864
A0A1V6NQP0
Histone-lysine N-methyltransferase, H3 lysine-4 specific; Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation.
    
 0.854
A0A1V6NFP7
BZIP domain-containing protein.
    
 0.802
A0A1V6NKL8
Uncharacterized protein.
    
 0.802
A0A1V6NAH9
Histone domain-containing protein.
    
 0.798
A0A1V6NPH7
Histone H3; Belongs to the histone H3 family.
    
 0.798
A0A1V6N6S9
Histone H2A; Belongs to the histone H2A family.
   
 0.777
A0A1V6NPL1
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
  0.727
Your Current Organism:
Penicillium polonicum
NCBI taxonomy Id: 60169
Other names: CBS 222.28, IBT 12821, IMI 291194, MUCL 29204, NRRL 995, P. polonicum, Penicillium aurantiogriseum var. polonicum, Penicillium aurantiogriseum var. polonicum (W.Zalessky) Frisvad & Filt
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.