STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A1V6P1N9Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (193 aa)    
Predicted Functional Partners:
A0A1V6N6T9
Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
   
 0.999
A0A1V6NSX1
Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
   
 0.999
A0A1V6NHZ1
Uncharacterized protein; Belongs to the actin family.
   
 0.998
A0A1V6N9S1
Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.
   
 0.997
A0A1V6NGL6
Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family.
   
 0.997
A0A1V6NHX5
Uncharacterized protein.
   
 0.986
A0A1V6NH41
WH1 domain-containing protein.
    
 0.979
A0A1V6NKE1
DUF2013 domain-containing protein.
    
 0.976
A0A1V6N9U7
Uncharacterized protein.
    
 0.898
A0A1V6NK34
Uncharacterized protein; Belongs to the actin family.
    
 0.894
Your Current Organism:
Penicillium polonicum
NCBI taxonomy Id: 60169
Other names: CBS 222.28, IBT 12821, IMI 291194, MUCL 29204, NRRL 995, P. polonicum, Penicillium aurantiogriseum var. polonicum, Penicillium aurantiogriseum var. polonicum (W.Zalessky) Frisvad & Filt
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