STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A1R3RWE1Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy. (172 aa)    
Predicted Functional Partners:
A0A1R3R8D2
Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy wh [...]
    
 0.999
A0A1R3RE52
Autophagy-related protein 3.
    
 0.999
A0A1R3RNT1
Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation.
   
 0.999
A0A1R3RSL4
ATG16 domain-containing protein.
    
 0.984
A0A1R3RSK3
Uncharacterized protein.
    
 0.983
A0A1R3RNY2
Autophagy-related protein.
   
 0.980
A0A1R3R6V6
Lipase_3 domain-containing protein.
   
 
 0.977
A0A1R3RUV9
Uncharacterized protein.
    
 
 0.975
A0A1R3RR88
Uncharacterized protein.
    
 0.972
A0A1R3RR49
Autophagy_act_C domain-containing protein.
    
 0.909
Your Current Organism:
Aspergillus carbonarius
NCBI taxonomy Id: 602072
Other names: A. carbonarius ITEM 5010, Aspergillus carbonarius ITEM 5010
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