Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TSIB_0084Putative transcriptional regulatory protein. (148 aa)    
Predicted Functional Partners:
TSIB_0533
Predicted ATPase, PP-loop superfamily.
  
     0.616
TSIB_1358
DUF555 domain containing protein; Belongs to the UPF0212 family.
  
     0.604
TSIB_0981
Phosphoesterase, putative.
  
     0.560
TSIB_0725
Predicted membrane protein.
  
     0.553
TSIB_0780
Flagella accessory protein.
  
     0.549
TSIB_0604
DNA-directed RNA polymerase, subunit F.
 
     0.546
TSIB_0782
Archaeal flagella-related protein H, predicted ATPase.
  
     0.530
TSIB_0011
Hypothetical protein.
  
     0.524
pelA
Cell division like protein pelota; May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity.
 
    0.521
TSIB_0786
Probable flagellin; Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella.
  
     0.504
Your Current Organism:
Thermococcus sibiricus
NCBI taxonomy Id: 604354
Other names: T. sibiricus MM 739, Thermococcus sibiricus MM 739, Thermococcus sibiricus str. MM 739, Thermococcus sibiricus strain MM 739
Server load: low (16%) [HD]