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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TSIB_0127DUF59 domain containing protein. (108 aa)    
Predicted Functional Partners:
bpsA
Predicted methyltransferase; Involved in the biosynthesis of branched-chain polyamines, which support the growth of thermophiles under high-temperature conditions. Catalyzes the sequential condensation of spermidine with the aminopropyl groups of decarboxylated S-adenosylmethionines to produce N(4)-bis(aminopropyl)spermidine via N(4)-aminopropylspermidine.
       0.681
TSIB_0128
4Fe-4S ferredoxin.
       0.605
TSIB_1721
ABC-type transport system involved in Fe-S cluster assembly, ATPase component.
 
  
 0.547
TSIB_0193
Probable cysteine desulfurase.
 
  
 0.488
TSIB_1673
PaaI related protein, phenylacetic acid degradation-related.
  
  
 0.471
TSIB_1693
ABC transporter, ATP-binding protein.
 
  
 0.470
TSIB_0800
Acetyl-CoA acetyltransferase.
  
  
 0.438
TSIB_0911
Aminotransferase, class-V.
 
  
 0.438
dphB
Diphthine synthase; S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis.
       0.436
SufB
SufB; FeS assembly protein SufB.
 
   
 0.430
Your Current Organism:
Thermococcus sibiricus
NCBI taxonomy Id: 604354
Other names: T. sibiricus MM 739, Thermococcus sibiricus MM 739, Thermococcus sibiricus str. MM 739, Thermococcus sibiricus strain MM 739
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