STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TSIB_0149Phosphomannomutase-related protein. (238 aa)    
Predicted Functional Partners:
TSIB_0150
Nucleotidyl transferase family.
 
  
 0.887
tmk
Probable thymidylate kinase.
     
 0.786
pckG
Phosphoenolpyruvate carboxykinase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
     
 0.687
TSIB_2019
Pyrophosphorylase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
 
 0.624
TSIB_1274
Bifunctional phosphatase/dolichol-phosphate glucosyltransferase.
  
 
 0.601
dacZ
Hypothetical protein; Diadenylate cyclase that catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP is a second messenger for intracellular signal transduction involved in the control of important regulatory processes such as osmoregulation.
   
 
 0.584
TSIB_0833
Kef-type K+ transport systems, predicted NAD-binding component.
 
     0.511
TSIB_1831
RNA-binding protein, containing PUA domain.
  
     0.510
TSIB_1667
Radical SAM family protein.
 
   
 0.493
TSIB_1772
SAM-dependent methyltransferase, putative.
 
    0.480
Your Current Organism:
Thermococcus sibiricus
NCBI taxonomy Id: 604354
Other names: T. sibiricus MM 739, Thermococcus sibiricus MM 739, Thermococcus sibiricus str. MM 739, Thermococcus sibiricus strain MM 739
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.