Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
cpgSCyclic 2,3-diphospoglycerate synthetase; Catalyzes the formation of cyclic 2,3-diphosphoglycerate (cDPG) by formation of an intramolecular phosphoanhydride bond at the expense of ATP. (434 aa)    
Predicted Functional Partners:
pgk2
2-phosphoglycerate kinase.
 
   
 0.962
TSIB_0157
Predicted phosphohydrolase.
 
     0.841
TSIB_0158
Inosine-5'-monophosphate dehydrogenase related.
       0.629
TSIB_0161
ABC-type molybdate transport system, periplasmic component.
       0.592
TSIB_0270
Putative membrane-bound dolichyl-phosphate-mannose-protein mannosyltransferase.
  
     0.579
TSIB_0434
RNA-binding protein, containing KH domain.
  
     0.521
TSIB_1336
Putative tRNA-binding protein.
  
     0.511
TSIB_0162
ABC-type sulfate transport system, permease component.
       0.503
TSIB_0163
ABC transporter, ATP-binding protein.
       0.470
TSIB_1343
Probable brix domain-containing ribosomal biogenesis protein; Probably involved in the biogenesis of the ribosome.
  
     0.470
Your Current Organism:
Thermococcus sibiricus
NCBI taxonomy Id: 604354
Other names: T. sibiricus MM 739, Thermococcus sibiricus MM 739, Thermococcus sibiricus str. MM 739, Thermococcus sibiricus strain MM 739
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