Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Gene Fusion
Co-occurrence
Co-expression
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[Homology]
Score
TSIB_0176Phosphoribosyl transferase domain protein. (215 aa)    
Predicted Functional Partners:
TSIB_0177
Hypothetical protein.
       0.885
TSIB_0175
ArgE/DapE-related deacylase.
       0.584
TSIB_0178
ABC transporter, periplasmic binding protein.
 
     0.568
TSIB_0440
Orotidine 5'-phosphate decarboxylase.
     
 0.559
cysS
Cysteinyl-tRNA synthetase.
 
     0.558
rnhB
Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.
  
   
 0.461
TSIB_0612
3-hydroxy-3-methylglutaryl-coenzyme A reductase; Belongs to the HMG-CoA reductase family.
      
 0.428
TSIB_1394
Hypothetical protein.
  
     0.417
TSIB_0744
Hypothetical protein; Involved in DNA damage repair; Belongs to the Nre family.
  
     0.415
TSIB_1427
Adenine phosphoribosyltransferase, fused to N-terminal DNA-binding domain.
 
 
 0.403
Your Current Organism:
Thermococcus sibiricus
NCBI taxonomy Id: 604354
Other names: T. sibiricus MM 739, Thermococcus sibiricus MM 739, Thermococcus sibiricus str. MM 739, Thermococcus sibiricus strain MM 739
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