Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TSIB_0189Hypothetical protein. (266 aa)    
Predicted Functional Partners:
TSIB_0188
dephospho-CoA kinase.
       0.885
TSIB_0190
Hypothetical protein.
       0.885
TSIB_0187
DUF2297 domain containing protein.
       0.873
TSIB_0195
Hypothetical protein.
       0.715
TSIB_0191
Hypothetical protein.
       0.528
TSIB_0192
Hypothetical protein.
       0.471
TSIB_0889
DUF104 domain containing protein.
       0.429
pyrI
Aspartate carbamoyltransferase regulatory chain; Involved in allosteric regulation of aspartate carbamoyltransferase.
       0.415
vapC
Predicted nucleic acid-binding protein, containing PIN domain; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family.
       0.415
pyrB
Aspartate carbamoyltransferase.
       0.400
Your Current Organism:
Thermococcus sibiricus
NCBI taxonomy Id: 604354
Other names: T. sibiricus MM 739, Thermococcus sibiricus MM 739, Thermococcus sibiricus str. MM 739, Thermococcus sibiricus strain MM 739
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