Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TSIB_0220Fructose-1,6-bisphosphate aldolase (FBA). (353 aa)    
Predicted Functional Partners:
TSIB_0221
ABC transporter, permease protein.
 
 
 0.991
TSIB_0222
ABC-type iron(III) transport system, periplasmic component.
 
  
  0.979
TSIB_0924
ABC-type dipeptide transport system, ATPase component.
 
     
0.892
TSIB_0219
DUF447 domain containing protein.
       0.880
TSIB_0162
ABC-type sulfate transport system, permease component.
   0.849
TSIB_0332
Cellobiose/beta-glucoside ABC transporter, ATPase component CbtD.
 
    
0.729
TSIB_0218
Metallophosphoesterase, calcineurin superfamily.
       0.718
TSIB_0360
Trehalose/maltose ABC transporter, permease component.
 
   
 0.681
TSIB_1983
Daunorubicin resistance ATP-binding protein DrrA.
 
    
0.679
TSIB_0359
Trehalose/maltose ABC transporter, permease component.
 
   
 0.654
Your Current Organism:
Thermococcus sibiricus
NCBI taxonomy Id: 604354
Other names: T. sibiricus MM 739, Thermococcus sibiricus MM 739, Thermococcus sibiricus str. MM 739, Thermococcus sibiricus strain MM 739
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