Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
TSIB_0285NiFe hydrogenase I, catalytic subunit alpha. (427 aa)    
Predicted Functional Partners:
TSIB_0284
NiFe hydrogenase I, subunit delta.
 
 0.999
TSIB_0282
NiFe hydrogenase I, subunit beta.
 
 
 0.997
TSIB_0283
NiFe hydrogenase I, subunit gamma.
 
 
 0.997
TSIB_1522
NiFe hydrogenase II, subunit delta.
 
 0.996
TSIB_1520
NiFe hydrogenase II, subunit beta.
 
 
 0.988
TSIB_1521
NiFe hydrogenase II, subunit gamma.
 
 
 0.984
hypA
Probable hydrogenase nickel incorporation protein hypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
 
 0.914
TSIB_1523
NiFe hydrogenase II, catalytic subunit alpha.
  
  
 
0.908
TSIB_1361
Cysteine synthase.
    
  0.903
TSIB_1518
NADH:ubiquinone oxidoreductase, NADH-binding subunit F.
  
 
 0.888
Your Current Organism:
Thermococcus sibiricus
NCBI taxonomy Id: 604354
Other names: T. sibiricus MM 739, Thermococcus sibiricus MM 739, Thermococcus sibiricus str. MM 739, Thermococcus sibiricus strain MM 739
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