Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
TSIB_0286Hydrogenase-specific maturation endopeptidase. (151 aa)    
Predicted Functional Partners:
TSIB_0284
NiFe hydrogenase I, subunit delta.
 
  
 0.917
TSIB_0282
NiFe hydrogenase I, subunit beta.
 
     0.884
TSIB_0285
NiFe hydrogenase I, catalytic subunit alpha.
 
  
 0.869
TSIB_0283
NiFe hydrogenase I, subunit gamma.
  
    0.866
TSIB_1523
NiFe hydrogenase II, catalytic subunit alpha.
 
  
 0.653
rpl2
50S ribosomal protein L2P; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.
 
     0.565
TSIB_1518
NADH:ubiquinone oxidoreductase, NADH-binding subunit F.
  
  
 0.563
rpl29
50S ribosomal protein L29P; Belongs to the universal ribosomal protein uL29 family.
 
     0.544
rpl4
50S ribosomal protein L4P; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
   
   0.535
TSIB_1002
Hydrogenase maturation protease.
  
   
 0.530
Your Current Organism:
Thermococcus sibiricus
NCBI taxonomy Id: 604354
Other names: T. sibiricus MM 739, Thermococcus sibiricus MM 739, Thermococcus sibiricus str. MM 739, Thermococcus sibiricus strain MM 739
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