Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
TSIB_0502FeoB ferrous iron transport protein B - like protein. (681 aa)    
Predicted Functional Partners:
TSIB_0501
Fe2+ transport protein, putative.
  
  
 0.989
TSIB_0503
LexA-related DNA-binding protein.
       0.882
TSIB_1895
Rubredoxin; Rubredoxin is a small nonheme, iron protein lacking acid- labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule.
     
 0.852
gap
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH).
     
 0.845
TSIB_0504
NDP-sugar synthase.
  
    0.814
TSIB_0500
Hypothetical protein.
     
 0.769
TSIB_1184
Hydrogenase expression/formation protein HypE.
       0.644
TSIB_1721
ABC-type transport system involved in Fe-S cluster assembly, ATPase component.
     
 0.594
TSIB_0121
Manganese-dependent transcription regulator.
 
  
 0.542
TSIB_1704
Heavy-metal transporting P-type ATPase.
  
 
 0.526
Your Current Organism:
Thermococcus sibiricus
NCBI taxonomy Id: 604354
Other names: T. sibiricus MM 739, Thermococcus sibiricus MM 739, Thermococcus sibiricus str. MM 739, Thermococcus sibiricus strain MM 739
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