Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
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[Homology]
Score
TSIB_0613Cell division inhibitor minD like protein. (252 aa)    
Predicted Functional Partners:
TSIB_0612
3-hydroxy-3-methylglutaryl-coenzyme A reductase; Belongs to the HMG-CoA reductase family.
       0.880
TSIB_0615
Probable L-threonine 3-dehydrogenase.
       0.761
pheS
Phenylalanyl-tRNA synthetase alpha chain; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.
       0.705
pheT
Phenylalanyl-tRNA synthetase beta chain.
       0.568
TSIB_0614
Predicted RNA-binding protein, containing TRAM domain.
       0.563
atpC
A1A0 ATP synthase, subunit C; Produces ATP from ADP in the presence of a proton gradient across the membrane.
 
   
 0.488
engB
Probable GTP-binding protein; Necessary for normal cell division and for the maintenance of normal septation.
 
   
 0.482
TSIB_1335
Pfam01068, DNA_ligase_A_M, ATP dependent DNA ligase domain.
     
 0.401
TSIB_1796
A1A0 ATP synthase, subunit c.
     
 0.400
Your Current Organism:
Thermococcus sibiricus
NCBI taxonomy Id: 604354
Other names: T. sibiricus MM 739, Thermococcus sibiricus MM 739, Thermococcus sibiricus str. MM 739, Thermococcus sibiricus strain MM 739
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