Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
TSIB_0637Dye-L-proDH alpha. (477 aa)    
Predicted Functional Partners:
TSIB_0638
Dye-linked L-proline dehydrogenase gamma2 subunit.
   
 0.996
TSIB_0640
Dye-linked L-proline dehydrogenase beta2 subunit.
 
 0.988
TSIB_0639
Proline dehydrogenase, delta subunit.
 
   
 0.968
TSIB_0636
Sarcosine oxidase, beta subunit.
 
 0.966
gcvT
Probable aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine.
    
 0.906
TSIB_0635
Sarcosine oxidase, alpha subunit.
 
    
0.723
TSIB_0771
Predicted dehydrogenase.
   
 0.585
TSIB_0641
Hypothetical protein.
       0.450
pyrH
Probable uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
  
    0.414
TSIB_1816
Carbon-nitrogen hydrolase.
   
  
 0.410
Your Current Organism:
Thermococcus sibiricus
NCBI taxonomy Id: 604354
Other names: T. sibiricus MM 739, Thermococcus sibiricus MM 739, Thermococcus sibiricus str. MM 739, Thermococcus sibiricus strain MM 739
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