Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
TSIB_0638Dye-linked L-proline dehydrogenase gamma2 subunit. (168 aa)    
Predicted Functional Partners:
TSIB_0637
Dye-L-proDH alpha.
   
 0.996
TSIB_0639
Proline dehydrogenase, delta subunit.
 
   
 0.966
TSIB_0640
Dye-linked L-proline dehydrogenase beta2 subunit.
 
  
 0.964
TSIB_0635
Sarcosine oxidase, alpha subunit.
 
   
 0.899
TSIB_0636
Sarcosine oxidase, beta subunit.
 
  
 0.897
TSIB_1282
Membrane-bound hydrogenase MBH 2, subunit Mbh2N (hydrogenase subunit).
 
 
 0.655
TSIB_1296
Membrane-bound hydrogenase MBH 1, subunit Mbh1N (hydrogenase subunit).
  
 
 0.655
hypA
Probable hydrogenase nickel incorporation protein hypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
  
  
 0.632
TSIB_1905
Membrane-bound NADP+-reducing complex MBX, subunit MbxN (dehydrogenase subunit).
  
 
 0.601
TSIB_1517
Glutamate synthase beta chain-related oxidoreductase, containing 2Fe- 2S and 4Fe-4S clusters.
   
 
 0.503
Your Current Organism:
Thermococcus sibiricus
NCBI taxonomy Id: 604354
Other names: T. sibiricus MM 739, Thermococcus sibiricus MM 739, Thermococcus sibiricus str. MM 739, Thermococcus sibiricus strain MM 739
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