Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
TSIB_0702Hydrolase, metallo-beta-lactamase superfamily. (273 aa)    
Predicted Functional Partners:
TSIB_0700
Iron-molybdenum cofactor-binding protein.
 
     0.921
mptE
Hypothetical protein; Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6-hydroxymethyl- 7,8-dihydropterin diphosphate (6-HMDP).
    
  0.903
TSIB_0666
Dihydropteroate synthase.
    
  0.900
TSIB_0701
Hypothetical protein.
       0.778
TSIB_0703
Short-chain alcohol dehydrogenase.
       0.756
TSIB_0698
Iron-molybdenum cofactor-binding protein.
 
     0.698
TSIB_0691
ATPase, ParA/MinD family, containing ferredoxin domains.
 
   
 0.609
TSIB_0690
ATPase, ParA/MinD family, containing ferredoxin domains.
 
   
 0.581
TSIB_1691
Iron-molybdenum cofactor-binding protein.
 
     0.574
TSIB_0687
DUF134 multi-domain protein; Belongs to the UPF0251 family.
 
     0.545
Your Current Organism:
Thermococcus sibiricus
NCBI taxonomy Id: 604354
Other names: T. sibiricus MM 739, Thermococcus sibiricus MM 739, Thermococcus sibiricus str. MM 739, Thermococcus sibiricus strain MM 739
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