Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
TSIB_0727UPF0179 domain containing protein; Belongs to the UPF0179 family. (142 aa)    
Predicted Functional Partners:
egsA
Glycerol-1-phosphate dehydrogenase NAD(P); Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1- phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea. Belongs to the glycerol-1-phosphate dehydrogenase family.
 
   
 0.917
TSIB_0725
Predicted membrane protein.
 
   
 0.908
TSIB_0724
Archaeal inositol-1-monophosphatase/fructose-1, 6-bisphosphatase.
 
     0.834
TSIB_1831
RNA-binding protein, containing PUA domain.
  
     0.711
TSIB_1473
Predicted Fe-S oxidoreductase.
  
     0.697
TSIB_0604
DNA-directed RNA polymerase, subunit F.
 
     0.666
TSIB_0834
Inosine-5'-monophosphate dehydrogenase related protein III.
  
     0.643
TSIB_0314
DUF106 domain containing protein.
  
     0.636
rpl40e
50S ribosomal protein L40e; Belongs to the eukaryotic ribosomal protein eL40 family.
  
     0.629
TSIB_1094
Archaea-specific Zn-finger-containing protein.
  
     0.618
Your Current Organism:
Thermococcus sibiricus
NCBI taxonomy Id: 604354
Other names: T. sibiricus MM 739, Thermococcus sibiricus MM 739, Thermococcus sibiricus str. MM 739, Thermococcus sibiricus strain MM 739
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