Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TSIB_0804DNA binding helix-turn helix protein. (179 aa)    
Predicted Functional Partners:
rps3ae
30S ribosomal protein S3Ae; Belongs to the eukaryotic ribosomal protein eS1 family.
  
   0.875
rpl18e
50S ribosomal protein L18e; Belongs to the eukaryotic ribosomal protein eL18 family.
 
   0.874
rpl21e
50S ribosomal protein L21e; Belongs to the eukaryotic ribosomal protein eL21 family.
  
   0.862
rpl40e
50S ribosomal protein L40e; Belongs to the eukaryotic ribosomal protein eL40 family.
  
   0.849
rpl24e
50S ribosomal protein L24e; Binds to the 23S rRNA.
  
   0.848
rpl29
50S ribosomal protein L29P; Belongs to the universal ribosomal protein uL29 family.
  
 
 0.838
rps19e
30S ribosomal protein S19e; May be involved in maturation of the 30S ribosomal subunit. Belongs to the eukaryotic ribosomal protein eS19 family.
 
   0.836
TSIB_0803
N-acetyltransferase, GNAT family.
  
    0.835
rpl18
50S ribosomal protein L18P; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
 
   0.829
rpl19e
50S ribosomal protein L19e; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL19 family.
  
   0.820
Your Current Organism:
Thermococcus sibiricus
NCBI taxonomy Id: 604354
Other names: T. sibiricus MM 739, Thermococcus sibiricus MM 739, Thermococcus sibiricus str. MM 739, Thermococcus sibiricus strain MM 739
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