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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
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gene co-occurrence
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[Homology]
Score
TSIB_0813Phosphoglucose isomerase (PGI). (190 aa)    
Predicted Functional Partners:
glkA
ADP-dependent glucokinase (GLK); Catalyzes the ADP-dependent phosphorylation of D-glucose to D-glucose 6-phosphate and glucosamine to glucosamine 6-phosphate.
 
  
 0.979
TSIB_0428
Bifunctional D-arabino 3-hexulose-6-phosphate formaldehyde lyase/phosphohexuloisomerase.
 
 
  0.971
TSIB_0248
Phosphoglucomutase.
    
 0.942
pfkC
ADP-dependent 6-phosphofructokinase (PFK); Catalyzes the phosphorylation of fructose 6-phosphate to fructose 1,6-bisphosphate using ADP as the phosphate donor.
    
 0.942
TSIB_0249
Mannose-6-phosphate isomerase/mannose-1-phosphate guanylyl transferase; Belongs to the mannose-6-phosphate isomerase type 2 family.
    
  0.937
TSIB_0357
Sugar kinase; Belongs to the carbohydrate kinase PfkB family.
  
 
 0.907
glmS
Glucosamine-fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
    
 0.904
fbp
Fructose-1,6-bisphosphatase (FBP); Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P).
    
 0.904
tpiA
Triosephosphate isomerase (TIM); Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
 
  
 0.900
TSIB_0230
Fructose-1,6-bisphosphate aldolase (FBA).
 
  
 0.889
Your Current Organism:
Thermococcus sibiricus
NCBI taxonomy Id: 604354
Other names: T. sibiricus MM 739, Thermococcus sibiricus MM 739, Thermococcus sibiricus str. MM 739, Thermococcus sibiricus strain MM 739
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