Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TSIB_0818Hypothetical protein. (119 aa)    
Predicted Functional Partners:
TSIB_0817
Hypothetical protein.
       0.773
TSIB_0820
Predicted acetone carboxylase, subunit beta.
       0.533
TSIB_0819
Predicted acetone carboxylase, subunit alpha.
       0.523
TSIB_0816
DUF88 domain containing protein.
       0.511
TSIB_0821
Xaa-Pro aminopeptidase; Belongs to the peptidase M24B family.
       0.494
TSIB_1274
Bifunctional phosphatase/dolichol-phosphate glucosyltransferase.
  
  
 0.489
TSIB_0822
Permease for cytosine/purines, uracil, thiamine, allantoin.
       0.481
TSIB_1823
Dolichol-phosphate mannosyltransferase, fused to membrane-bound GtrA- like domain.
  
  
 0.470
TSIB_2047
RfbC dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
  
  
 0.452
TSIB_2048
dTDP 4-dehydrorhamnose reductase.
  
  
 0.433
Your Current Organism:
Thermococcus sibiricus
NCBI taxonomy Id: 604354
Other names: T. sibiricus MM 739, Thermococcus sibiricus MM 739, Thermococcus sibiricus str. MM 739, Thermococcus sibiricus strain MM 739
Server load: low (12%) [HD]