Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pdaDPyruvoyl-dependent arginine decarboxylase; Belongs to the PdaD family. (158 aa)    
Predicted Functional Partners:
TSIB_0246
Agmatinase; Belongs to the arginase family.
 
  
 0.928
TSIB_1067
Arginase; Belongs to the arginase family.
    
 0.921
TSIB_0427
Arginase; Belongs to the arginase family.
    
 0.918
speE
Probable spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine; Belongs to the spermidine/spermine synthase family.
  
 
 0.820
TSIB_0848
NapA-type sodium/hydrogen antiporter.
       0.789
speH
S-adenosylmethionine decarboxylase proenzyme; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
  
  
 0.784
TSIB_0612
3-hydroxy-3-methylglutaryl-coenzyme A reductase; Belongs to the HMG-CoA reductase family.
      
 0.717
TSIB_0440
Orotidine 5'-phosphate decarboxylase.
     
 0.550
TSIB_1704
Heavy-metal transporting P-type ATPase.
      
 0.545
TSIB_1712
Mercury ion binding protein.
  
   
 0.498
Your Current Organism:
Thermococcus sibiricus
NCBI taxonomy Id: 604354
Other names: T. sibiricus MM 739, Thermococcus sibiricus MM 739, Thermococcus sibiricus str. MM 739, Thermococcus sibiricus strain MM 739
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