Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TSIB_0857Hypothetical protein. (219 aa)    
Predicted Functional Partners:
TSIB_0854
Putative ABC transporter.
       0.885
TSIB_0855
Glycosyl transferase.
       0.885
TSIB_0853
4-hydroxybenzoate octaprenyltransferase.
       0.861
TSIB_0858
Hypothetical protein.
       0.846
TSIB_0856
Putative amidase.
       0.836
TSIB_0859
Nucleic acid-binding protein, containing C2H2 zinc-finger.
       0.680
speE
Probable spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine; Belongs to the spermidine/spermine synthase family.
       0.644
TSIB_0852
Putative HTH transcription regulator.
       0.608
Your Current Organism:
Thermococcus sibiricus
NCBI taxonomy Id: 604354
Other names: T. sibiricus MM 739, Thermococcus sibiricus MM 739, Thermococcus sibiricus str. MM 739, Thermococcus sibiricus strain MM 739
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