Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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TSIB_0918TRNA/rRNA cytosine-C5-methylase, NOL1/NOP2/Sun family, fused to N- terminal NusB regulator domain; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (450 aa)    
Predicted Functional Partners:
TSIB_1961
GTPase, MMR1/HSR1 family.
 
 
 0.771
TSIB_1805
Hypothetical protein.
  
 
 0.752
TSIB_0919
DNA polymerase; Contains an intein.
  
  
 0.741
TSIB_0798
NOP5/NOP56 related protein.
   
 
 0.737
TSIB_1365
Predicted GTPase, containing NOG1 domain.
   
 
 0.737
rps8e
30S ribosomal protein S8e.
   
 
 0.657
tmcA
Predicted ATPase, DUF699 family, fused to acetyltransferase domain; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP).
  
 
 0.655
rpl18
50S ribosomal protein L18P; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
 
 
 0.629
rpl30
50S ribosomal protein L30P.
  
 
 0.625
rpl10
Acidic ribosomal like protein P0; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.
  
 
 0.624
Your Current Organism:
Thermococcus sibiricus
NCBI taxonomy Id: 604354
Other names: T. sibiricus MM 739, Thermococcus sibiricus MM 739, Thermococcus sibiricus str. MM 739, Thermococcus sibiricus strain MM 739
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