Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
TSIB_0955Predicted succinyl-CoA:3-ketoacid-CoA ligase. (546 aa)    
Predicted Functional Partners:
TSIB_0800
Acetyl-CoA acetyltransferase.
    
 0.931
TSIB_1384
Pyruvate:ferredoxin oxidoreductase (POR) and 2-ketoisovalerate:ferredoxin oxidoreductase (VOR) subunit gamma.
  
  
  0.911
TSIB_1380
Pyruvate:ferredoxin oxidoreductase (POR), subunit delta.
    
  0.902
TSIB_0147
Acetyl-CoA synthetase II (ACSII, ADP-forming), subunit alpha.
     
  0.900
TSIB_0206
Acetate---CoA ligase (ADP-forming) subunit beta; Acetyl-CoA synthetase II (ACSII, ADP-forming) and succinyl-CoA synthetase (SCS, ADP-forming), subunit beta.
     
  0.900
TSIB_0207
Acyl-CoA synthetase, subunit alpha.
     
  0.900
TSIB_0529
Acetyl-CoA synthetase I (ACSI, ADP-forming), subunit alpha.
     
  0.900
TSIB_1099
Acetyl-CoA synthetase I (ACSI, ADP-forming), subunit beta.
     
  0.900
TSIB_1163
Acylphosphatase.
     
  0.900
TSIB_1378
Pyruvate:ferredoxin oxidoreductase (POR), subunit beta.
     
  0.900
Your Current Organism:
Thermococcus sibiricus
NCBI taxonomy Id: 604354
Other names: T. sibiricus MM 739, Thermococcus sibiricus MM 739, Thermococcus sibiricus str. MM 739, Thermococcus sibiricus strain MM 739
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