STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TSIB_1016D-isomer specific 2-hydroxyacid dehydrogenase. (333 aa)    
Predicted Functional Partners:
TSIB_1605
Putative glycerate kinase.
 
 0.938
TSIB_1433
Alanine aminotransferase.
 
  
 0.924
TSIB_0023
Putative sugar-catabolism phosphotransferase.
  
 
 0.922
TSIB_0439
Phosphoglycolate phosphatase; Catalyzes the dephosphorylation of 2-phosphoglycolate.
  
 
 0.916
TSIB_0549
Aspartate aminotransferase.
  
 
  0.907
TSIB_1279
Transaminase.
  
 
  0.907
TSIB_1280
Glyoxylate reductase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
  
 
0.906
proS
Prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
  
 
 0.847
TSIB_0136
Predicted permease.
 
     0.711
TSIB_0137
Endoglucanase (intracellular).
       0.644
Your Current Organism:
Thermococcus sibiricus
NCBI taxonomy Id: 604354
Other names: T. sibiricus MM 739, Thermococcus sibiricus MM 739, Thermococcus sibiricus str. MM 739, Thermococcus sibiricus strain MM 739
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