Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TSIB_1072N-acetyltransferase, GNAT family. (273 aa)    
Predicted Functional Partners:
TSIB_1071
Multimeric flavodoxin (WrbA) domain containing protein.
       0.655
TSIB_1968
ArsR family transcriptional regulator.
 
   
 0.613
TSIB_0582
Alpha-galactosidase.
  
     0.601
TSIB_0833
Kef-type K+ transport systems, predicted NAD-binding component.
  
    0.590
TSIB_1081
ABC transporter, ATP-binding protein.
 
 
   0.489
TSIB_1966
Transcriptional regulatory protein, arsR family.
 
   
 0.487
TSIB_1079
ABC transporter ATP-binding protein.
 
 
   0.461
TSIB_1164
Hypothetical protein.
  
     0.430
Your Current Organism:
Thermococcus sibiricus
NCBI taxonomy Id: 604354
Other names: T. sibiricus MM 739, Thermococcus sibiricus MM 739, Thermococcus sibiricus str. MM 739, Thermococcus sibiricus strain MM 739
Server load: low (18%) [HD]