STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TSIB_1200Transcription regulator, ArsR family. (199 aa)    
Predicted Functional Partners:
TSIB_1201
Inosine-5'-monophosphate dehydrogenase related protein II.
     
 0.844
albA
DNA/RNA-binding protein Alba; Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes; Belongs to the histone-like Alba family.
       0.700
TSIB_1358
DUF555 domain containing protein; Belongs to the UPF0212 family.
  
     0.616
TSIB_1198
Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
       0.548
TSIB_1165
DUF460 multi-domain protein.
 
     0.546
nusA
NusA like protein; Participates in transcription termination. Belongs to the NusA family.
 
   
 0.545
TSIB_1203
Hypothetical protein.
 
     0.539
TSIB_1095
Hypothetical protein.
  
     0.533
TSIB_0550
Predicted transcription regulator, containing DNA-binding HTH domain.
  
   
 0.510
TSIB_0725
Predicted membrane protein.
  
     0.505
Your Current Organism:
Thermococcus sibiricus
NCBI taxonomy Id: 604354
Other names: T. sibiricus MM 739, Thermococcus sibiricus MM 739, Thermococcus sibiricus str. MM 739, Thermococcus sibiricus strain MM 739
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.