Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TSIB_1263Transcriptional regulator. (108 aa)    
Predicted Functional Partners:
TSIB_1264
Putative regulatory protein.
     
 0.922
TSIB_1265
Predicted transcription regulator, Lrp/AsnC family.
 
  
 0.831
TSIB_1262
Predicted metalloprotease, containing Jab1/MPN domain.
       0.818
TSIB_1266
Integral membrane protein.
 
     0.659
TSIB_1261
Hypothetical protein.
       0.525
TSIB_0520
Small heat shock protein; Belongs to the small heat shock protein (HSP20) family.
 
   
 0.463
TSIB_1779
Predicted transcription regulator, helix-turn-helix family.
  
   
 0.458
TSIB_1608
Archaeal heat shock regulator, ArsR family.
  
   
 0.454
TSIB_1704
Heavy-metal transporting P-type ATPase.
 
  
 0.451
TSIB_0990
Predicted transcription regulator, ArsR family.
      
 0.431
Your Current Organism:
Thermococcus sibiricus
NCBI taxonomy Id: 604354
Other names: T. sibiricus MM 739, Thermococcus sibiricus MM 739, Thermococcus sibiricus str. MM 739, Thermococcus sibiricus strain MM 739
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