Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
pfdBPrefoldin subunit beta; Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding. (133 aa)    
Predicted Functional Partners:
pfdA
Prefoldin subunit alpha; Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.
 
 0.997
rpoP
DNA-directed RNA polymerase subunit P; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoP/eukaryotic RPC10 RNA polymerase subunit family.
  
  
 0.926
TSIB_1343
Probable brix domain-containing ribosomal biogenesis protein; Probably involved in the biogenesis of the ribosome.
 
    0.916
TSIB_1342
DUF2144 domain containing protein.
  
    0.893
TSIB_1337
Hypothetical protein.
   
   0.885
rpl37ae
50S ribosomal protein L37Ae.
  
  
 0.882
TSIB_1336
Putative tRNA-binding protein.
       0.879
TSIB_1338
Hypothetical protein.
       0.879
TSIB_1339
Predicted phosphohydrolase, DHH family.
       0.879
TSIB_1340
Hypothetical protein.
       0.879
Your Current Organism:
Thermococcus sibiricus
NCBI taxonomy Id: 604354
Other names: T. sibiricus MM 739, Thermococcus sibiricus MM 739, Thermococcus sibiricus str. MM 739, Thermococcus sibiricus strain MM 739
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