STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TSIB_1499HypE hydrogenase expression/formation protein. (336 aa)    
Predicted Functional Partners:
TSIB_1434
Ni-Fe hydrogenase maturation protein HypD.
 
 
 0.977
TSIB_1435
Ni-Fe hydrogenase maturation protein HypC.
 
 
 0.969
TSIB_1495
Hydrogenase maturation protein HypF.
 
 
 0.942
hypA
Probable hydrogenase nickel incorporation protein hypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
  
 0.674
TSIB_1498
Peptidase S26B, signal peptidase.
       0.555
TSIB_1523
NiFe hydrogenase II, catalytic subunit alpha.
 
   
 0.532
TSIB_1500
Hypothetical protein.
       0.508
TSIB_1497
Hypothetical protein.
       0.459
TSIB_0285
NiFe hydrogenase I, catalytic subunit alpha.
 
   
 0.433
TSIB_1518
NADH:ubiquinone oxidoreductase, NADH-binding subunit F.
     
 0.420
Your Current Organism:
Thermococcus sibiricus
NCBI taxonomy Id: 604354
Other names: T. sibiricus MM 739, Thermococcus sibiricus MM 739, Thermococcus sibiricus str. MM 739, Thermococcus sibiricus strain MM 739
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.