Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
TSIB_1608Archaeal heat shock regulator, ArsR family. (206 aa)    
Predicted Functional Partners:
TSIB_0520
Small heat shock protein; Belongs to the small heat shock protein (HSP20) family.
     
 0.796
TSIB_1831
RNA-binding protein, containing PUA domain.
  
     0.618
pfdA
Prefoldin subunit alpha; Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.
  
   
 0.606
TSIB_1832
Hypothetical protein.
  
     0.604
TSIB_0727
UPF0179 domain containing protein; Belongs to the UPF0179 family.
  
     0.587
TSIB_1242
DEAD/DEAH box RNA helicase.
  
     0.566
TSIB_1609
Glyoxalase II family member.
       0.565
mutS2
MutS-like DNA mismatch repair ATPase; Has ATPase and non-specific DNA-binding activities. Belongs to the DNA mismatch repair MutS family. Archaeal Muts2 subfamily.
  
     0.560
TSIB_1094
Archaea-specific Zn-finger-containing protein.
  
     0.558
TSIB_0604
DNA-directed RNA polymerase, subunit F.
  
     0.554
Your Current Organism:
Thermococcus sibiricus
NCBI taxonomy Id: 604354
Other names: T. sibiricus MM 739, Thermococcus sibiricus MM 739, Thermococcus sibiricus str. MM 739, Thermococcus sibiricus strain MM 739
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