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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
co-expression
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[Homology]
Score
TSIB_1640Branched-chain alpha-keto acid dehydrogenase subunit E2. (86 aa)    
Predicted Functional Partners:
TSIB_1638
Pyruvate dehydrogenase, beta subunit.
  
 0.922
TSIB_1641
Dihydrolipoyllysine-residue acetyltransferase component of pyruvatedehydrogenase complex (E2).
 
     0.907
TSIB_1639
Pyruvate dehydrogenase.
 
 0.874
TSIB_1646
Thiamine pyrophosphate-dependent dehydrogenase, E1 component beta subunit.
  
 0.843
TSIB_1642
Hypothetical protein.
       0.801
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P).
  
 0.766
TSIB_1643
ATP-NAD/AcoX kinase.
 
     0.738
TSIB_1647
Thiamine pyrophosphate-dependent dehydrogenase, E1 component alpha subunit.
  
 0.707
TSIB_1518
NADH:ubiquinone oxidoreductase, NADH-binding subunit F.
  
 
 0.636
gcvH
Probable glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
  
 0.605
Your Current Organism:
Thermococcus sibiricus
NCBI taxonomy Id: 604354
Other names: T. sibiricus MM 739, Thermococcus sibiricus MM 739, Thermococcus sibiricus str. MM 739, Thermococcus sibiricus strain MM 739
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