Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TSIB_1648Hypothetical protein. (262 aa)    
Predicted Functional Partners:
TSIB_1649
Radical SAM domain protein.
       0.788
TSIB_1650
DUF1624 multi-domain protein.
       0.564
TSIB_1651
Membrane protein.
       0.560
TSIB_1646
Thiamine pyrophosphate-dependent dehydrogenase, E1 component beta subunit.
       0.530
TSIB_1647
Thiamine pyrophosphate-dependent dehydrogenase, E1 component alpha subunit.
       0.530
TSIB_1645
2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase.
       0.495
TSIB_1644
Biotin/lipoate A/B protein ligase family protein.
       0.458
Your Current Organism:
Thermococcus sibiricus
NCBI taxonomy Id: 604354
Other names: T. sibiricus MM 739, Thermococcus sibiricus MM 739, Thermococcus sibiricus str. MM 739, Thermococcus sibiricus strain MM 739
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