STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TSIB_1653Predicted DNA methylase. (363 aa)    
Predicted Functional Partners:
TSIB_1343
Probable brix domain-containing ribosomal biogenesis protein; Probably involved in the biogenesis of the ribosome.
  
    0.701
TSIB_0265
Nonsense-mediated mRNA decay NMD3 like protein.
  
    0.642
TSIB_1654
Hypothetical protein.
       0.629
TSIB_0721
Predicted nucleic acid-binding protein, containing PIN domain.
  
    0.615
TSIB_1365
Predicted GTPase, containing NOG1 domain.
 
    0.594
tmcA
Predicted ATPase, DUF699 family, fused to acetyltransferase domain; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP).
   
  
 0.588
TSIB_0929
SAM-dependent methyltransferase, putative.
   
  
 0.575
TSIB_0731
Hypothetical protein.
  
    0.569
rsmA
Probable dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
  
  
 0.556
TSIB_0188
dephospho-CoA kinase.
  
     0.541
Your Current Organism:
Thermococcus sibiricus
NCBI taxonomy Id: 604354
Other names: T. sibiricus MM 739, Thermococcus sibiricus MM 739, Thermococcus sibiricus str. MM 739, Thermococcus sibiricus strain MM 739
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.