Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
TSIB_1697Cobalt/zinc/cadmium cation efflux pump protein. (296 aa)    
Predicted Functional Partners:
TSIB_1696
Iron-molybdenum cofactor-binding protein.
       0.855
TSIB_1698
Predicted stress-inducible protein, OsmC/Ohr family.
 
     0.640
TSIB_1891
Heavy-metal cation transporter, ZIP family.
 
 0.587
TSIB_1144
Cobalt/zinc/cadmium cation efflux pump protein.
 
 
0.568
TSIB_1704
Heavy-metal transporting P-type ATPase.
  
  
 0.543
TSIB_1797
A1A0 ATP synthase, subunit a; Belongs to the V-ATPase 116 kDa subunit family.
   
 
 0.538
hypA
Probable hydrogenase nickel incorporation protein hypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
     
 0.518
TSIB_1003
Nucleotide-binding protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.
  
  
 0.422
TSIB_1010
CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
  
    0.421
Your Current Organism:
Thermococcus sibiricus
NCBI taxonomy Id: 604354
Other names: T. sibiricus MM 739, Thermococcus sibiricus MM 739, Thermococcus sibiricus str. MM 739, Thermococcus sibiricus strain MM 739
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