Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
TSIB_1772SAM-dependent methyltransferase, putative. (248 aa)    
Predicted Functional Partners:
TSIB_1773
Succinyl-diaminopimelate desuccinylase.
 
   
 0.886
TSIB_1559
Hypothetical protein.
 
     0.704
TSIB_1775
Metal dependent hydrolase.
 
  
 0.689
TSIB_1774
Oligopeptide transporter, OPT family.
       0.661
rps5
30S ribosomal protein S5P; With S4 and S12 plays an important role in translational accuracy.
    
 0.541
TSIB_1668
Predicted ATPase of the PP-loop superfamily.
 
 
 0.538
pfkC
ADP-dependent 6-phosphofructokinase (PFK); Catalyzes the phosphorylation of fructose 6-phosphate to fructose 1,6-bisphosphate using ADP as the phosphate donor.
  
     0.511
TSIB_0167
Hypothetical protein.
  
 0.479
TSIB_0693
DUF364 domain containing protein.
  
    0.478
TSIB_0149
Phosphomannomutase-related protein.
 
     0.474
Your Current Organism:
Thermococcus sibiricus
NCBI taxonomy Id: 604354
Other names: T. sibiricus MM 739, Thermococcus sibiricus MM 739, Thermococcus sibiricus str. MM 739, Thermococcus sibiricus strain MM 739
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