Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TSIB_1799Trk-type pottasium transport system, NAD-binding component. (231 aa)    
Predicted Functional Partners:
TSIB_1504
Trk-type pottasium transport system, membrane componen.
 
 
 0.968
secD
SecD protein-export membrane protein; Involved in protein export.
 
     0.911
secF
Protein-export membrane protein SecF; Involved in protein export.
       0.885
TSIB_1856
Molybdopterin-converting factor subunit 2.
  
    0.853
TSIB_1796
A1A0 ATP synthase, subunit c.
 
   
 0.851
speH-2
S-adenosylmethionine decarboxylase proenzyme; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
       0.827
TSIB_1797
A1A0 ATP synthase, subunit a; Belongs to the V-ATPase 116 kDa subunit family.
       0.800
TSIB_1798
A1A0 ATP synthase, subunit H.
       0.800
atpB
A1A0 ATP synthase, subunit B; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit.
       0.775
atpF
A1A0 ATP synthase, subunit F; Produces ATP from ADP in the presence of a proton gradient across the membrane.
       0.775
Your Current Organism:
Thermococcus sibiricus
NCBI taxonomy Id: 604354
Other names: T. sibiricus MM 739, Thermococcus sibiricus MM 739, Thermococcus sibiricus str. MM 739, Thermococcus sibiricus strain MM 739
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.