Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TSIB_18504-oxalocrotonate tautomerase, putative. (65 aa)    
Predicted Functional Partners:
TSIB_1729
4-oxalocrotonate tautomerase, putative.
     
 
0.900
TSIB_1851
Fe-S oxidoreductase.
       0.757
TSIB_1849
Hypothetical protein.
       0.628
TSIB_0163
ABC transporter, ATP-binding protein.
   
    0.544
TSIB_1848
Hypothetical protein.
       0.467
TSIB_1852
Predicted transcription regulator, MarR family; Belongs to the GbsR family.
       0.439
TSIB_1746
Glutaredoxin/thioredoxin-like protein.
  
     0.412
Your Current Organism:
Thermococcus sibiricus
NCBI taxonomy Id: 604354
Other names: T. sibiricus MM 739, Thermococcus sibiricus MM 739, Thermococcus sibiricus str. MM 739, Thermococcus sibiricus strain MM 739
Server load: low (22%) [HD]